Case Report

Adult-Onset Still's Disease: A Rare Cause of Pyrexia of Unknown Origin (Case Report with Literature Review)

Abstract

  • Adult-onset Still's disease (AOSD) is a remarkably rare illness. One well-known pathogenic process that results in systemic manifestations is auto-inflammatory disease. We report on a young man who complained of joint pain, sore throat, and a high spiking fever. After a thorough assessment using the Yamaguchi criteria, the patient's clinical examination, elevated serum ferritin and C-reactive protein (CRP), absence of serologic markers (RA factor, Antinuclear antibody levels), and lymphadenopathy all contributed to the diagnosis of AOSD. He was treated with analgesics, steroids, and disease-modifying anti-rheumatic drugs (DMARDs). Three weeks later, at the follow-up, his symptoms and lab parameters had improved.

  • Keywords: AOSD,Hyperferritinemia,DMARDs,PUO, Arthralgia



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